The investigation of antimicrobial and antifungal activity of some Artemisia L. species

Background : Throughout history pathogenic microorganisms cause infectious diseases. Medicinal herbs play an important role in human life because they are used for the therapy and production of herbal remedies. Therefore, it is relevant to study antibacterial activity medicinal including Artemisia L. species. Aim The purpose this was investigate antimicrobial antifungal species extracts identify their synergistic effects with erythromycin against skin isolates Staphylococcus aureus different mechanisms MLS-resistance. Materials methods absinthium herb (AAs-4, AAs-7, AAs-9), vulgaris (AV-4, AV-7, AV-9) abrotanum (AAr-4, AAr-7, AAr-9) were (solvents – 40%, 70% 90% ethyl alcohol respectively). determination performed using clinical antibiotic susceptible resistant microorganisms. Bacterial cultures identified on basis biochemical microtests “STAPHYtest 16”, “ENTEROtest 24”, “NEFERMENTtest 24” taking into account complex morphological cultural properties accordance recommendations 9 th edition “Bergey’s Manual Systematic Bacteriology”. Yeast-like fungi 40 tests help VITEK 2 system YST ID card. synergism investigated isolate non-inductive MLS-resistance mechanism (resistant at minimum bacteriostatic concentration 125 ?g/ml bactericidal 250 without induction resistance clindamycin). Research results evaluation carried out standard strains which recommended by WHO. conducted studies indicate that able reduce growth showed potent action cocci or rod-shaped microflora. directly depends ethanol as solvent. ethanol) extract (solvent show relation efflux obtained can be create drugs, well drugs (against gram-positive gram-negative bacteria).